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1

A comparison of the pharmacokinetics of antithrombin derived from human plasma and from transgenic goats and the prevention of sepsis in an animal model

Gerhard Dickneite

Journal:

Biopharmaceutics & Drug Disposition

Year:

2008

Language:

english

File:

PDF, 110 KB

english, 2008

2

The influence of aclacinomycin a on the immune response and on experimental immune disorders

Gerhard Dickneite, Roland Kurrle, Fritz R. Seiler, Gabriele Krajczewski, H.Harald Sedlacek

Journal:

International Journal of Immunopharmacology

Year:

1984

Language:

english

File:

PDF, 601 KB

english, 1984

3

Wound healing and degradation of the fibrin sealant Beriplast® P following partial liver resection in rabbits

Monika Kroez, Wiegand Lang, Gerhard Dickneite

Journal:

Wound Repair and Regeneration

Year:

2005

Language:

english

File:

PDF, 5.57 MB

english, 2005

4

Transepithelial Transport Properties of Peptidomimetic Thrombin Inhibitors in Monolayers of a Human Intestinal Cell Line (Caco-2) and Their Correlation toin VivoData

Elke Walter, Thomas Kissel, Martin Reers, Gerhard Dickneite, Dieter Hoffmann, Werner Stüber

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.05 MB

1995

5

Hypotension with intravenous immunoglobulin therapy: importance of pH and dimer formation

Monika Kroez, Ernst-Jürgen Kanzy, Peter Gronski, Gerhard Dickneite

Journal:

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

6

Prevention of Suture Hole Bleeding Using Fibrin Sealant: Benefits of Factor XIII

Gerhard Dickneite, Hubert Metzner, Uwe Nicolay

Journal:

Journal of Surgical Research

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

7

The Importance of Factor XIII as a Component of Fibrin Sealants

Gerhard Dickneite, Hubert J. Metzner, Monika Kroez, Berndt Hein, Uwe Nicolay

Journal:

Journal of Surgical Research

Year:

2002

Language:

english

File:

PDF, 305 KB

english, 2002

8

First-pass elimination of a peptidomimetic thrombin inhibitor is due to carrier-mediated uptake by the liver: Interaction with bile acid transport systems

Uta Eckhardt, Werner Stüber, Gerhard Dickneite, Martin Reersf, Ernst Petzinger

Journal:

Biochemical Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.21 MB

english, 1996

9

Differentiation of two catalytic sites on phosphorylase kinase for phosphorylase b and troponin T phosphorylation

Gerhard Dickneite, Herbert P. Jennissen, Ludwig M.G. Heilmeyer jr

Journal:

Year:

1978

Language:

english

File:

PDF, 432 KB

english, 1978

10

Critical Role of Factor XIII in the Initial Stages of Carbon Tetrachloride–Induced Adult Liver Remodeling

Ikuko Tsujimoto, Kei Moriya, Keiko Sakai, Gerhard Dickneite, Takao Sakai

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 4.00 MB

english, 2011

11

A comparison of fibrin sealants in relation to their in vitro and in vivo properties

Gerhard Dickneite, Hubert Metzner, Thomas Pfeifer, Monika Kroez, Günther Witzke

Journal:

Thrombosis Research

Year:

2003

Language:

english

File:

PDF, 490 KB

english, 2003

12

Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation

Gerhard Dickneite

Journal:

Thrombosis Research

Year:

2007

Language:

english

File:

PDF, 355 KB

english, 2007

13

Effects of prothrombin complex concentrate and recombinant activated factor VII on vitamin K antagonist induced anticoagulation

Kenichi A. Tanaka, Fania Szlam, Gerhard Dickneite, Jerrold H. Levy

Journal:

Thrombosis Research

Year:

2008

Language:

english

File:

PDF, 522 KB

english, 2008

14

Prothrombin complex concentrate (Beriplex P/N) for control of bleeding after kidney trauma in a rabbit dilutional coagulopathy model

Ingo Pragst, Franz Kaspereit, Bärbel Dörr, Gerhard Dickneite

Journal:

Thrombosis Research

Year:

2010

Language:

english

File:

PDF, 463 KB

english, 2010

15

The potentiation of human C1-inhibitor by dextran sulphate is transient in vivo: studies in a rat model

Ineke G.A.C. Bos, Gerard J. van Mierlo, Wim K. Bleeker, Gemma M.M. Rigter, Henk te Velthuis, Gerhard Dickneite, C.Erik Hack

Journal:

International Immunopharmacology

Year:

2001

Language:

english

File:

PDF, 175 KB

english, 2001

16

Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway

John W. Chen, Jose-Luiz Figueiredo, Gregory R. Wojtkiewicz, Cory Siegel, Yoshiko Iwamoto, Dong-Eog Kim, Marc W. Nolte, Gerhard Dickneite, Ralph Weissleder, Matthias Nahrendorf

Journal:

Journal of the American College of Cardiology: Cardiovascular Imaging

Year:

2012

Language:

english

File:

PDF, 3.12 MB

english, 2012

17

Impaired healing in factor XIII KO mice after myocardial infarction assessed by magnetic resonance imaging

Matthias Nahrendorf, Kai Hu, Karl-Heinz Hiller, Christiane Waller, Stefan Gattenlöhner, Gerhard Dickneite, Axel Haase, Wolfgang R. Bauer, Georg Ertl

Journal:

Journal of the American College of Cardiology

Year:

2002

Language:

english

File:

PDF, 374 KB

english, 2002

18

Substitution of coagulation factor XIII partially restores scar healing after myocardial infarction in factor XIII knockout mice

Matthias Nahrendorf, Kai Hu, Karl-Heinz Hiller, Christiane Waller, Stefan Gattenlöhner, Gerhard Dickneite, Axel Haase, Wolfgang R. Bauer, Georg Ertl

Journal:

Journal of the American College of Cardiology

Year:

2003

Language:

english

File:

PDF, 176 KB

english, 2003

19

Preclinical Studies with 15-Deoxyspergualin in Various Animal Models for Autoimmune Diseases

HANS-ULRICH SCHORLEMMER, GERHARD DICKNEITE

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

20

Preclinical efficacy and safety of rVIII-SingleChain (CSL627), a novel recombinant single-chain factor VIII

Zollner, Sabine B., Raquet, Elmar, Müller-Cohrs, Jochen, Metzner, Hubert J., Weimer, Thomas, Pragst, Ingo, Dickneite, Gerhard, Schulte, Stefan

Journal:

Thrombosis Research

Year:

2013

Language:

english

File:

PDF, 5.13 MB

english, 2013

21

Non-clinical pharmacokinetics and pharmacodynamics of rVIII-SingleChain, a novel recombinant single-chain factor VIII

Zollner, Sabine, Raquet, Elmar, Claar, Philipp, Müller-Cohrs, Jochen, Metzner, Hubert J., Weimer, Thomas, Pragst, Ingo, Dickneite, Gerhard, Schulte, Stefan

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 510 KB

english, 2014

22

Biodistribution of the recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) in rats

Herzog, Eva, Harris, Stephen, Henson, Claire, McEwen, Andrew, Schenk, Sabrina, Nolte, Marc W., Pragst, Ingo, Dickneite, Gerhard, Schulte, Stefan, Zollner, Sabine

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

23

Recombinant fusion protein linking factor VIIa with albumin (rVIIaFP): Tissue distribution in rats

Herzog, Eva, Harris, Stephen, McEwen, Andrew, Henson, Claire, Pragst, Ingo, Dickneite, Gerhard, Schulte, Stefan, Zollner, Sabine

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 717 KB

english, 2014

24

Prothrombin Complex Concentrates as Reversal Agents for New Oral Anticoagulants

Dickneite, Gerhard

Journal:

Clinics in Laboratory Medicine

Year:

2014

Language:

english

File:

PDF, 746 KB

english, 2014

25

Analysis of the safety and pharmacodynamics of human fibrinogen concentrate in animals

Beyerle, Andrea, Nolte, Marc W., Solomon, Cristina, Herzog, Eva, Dickneite, Gerhard

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 820 KB

english, 2014

26

Thrombotic safety of prothrombin complex concentrate (Beriplex P/N) for dabigatran reversal in a rabbit model

Herzog, Eva, Kaspereit, Franz J., Krege, Wilfried, Doerr, Baerbel, van Ryn, Joanne, Dickneite, Gerhard, Pragst, Ingo

Journal:

Thrombosis Research

Year:

2014

Language:

english

File:

PDF, 541 KB

english, 2014

27

Synthesis and Characterisation of Novel Thrombin Inhibitors Based on 4-Amidinophenylalanine

Reers, Martin, Koschinsky, Miner, Dickneite, Gerhard, Hoffmann, Dieter, Czech, JÖ, Stür, Werner

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 628 KB

english, 1995

28

Correlation of Coagulation Markers and 4F-PCC-Mediated Reversal of Rivaroxaban in a Rabbit Model of Acute Bleeding

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Mueller-Cohrs, Jochen, Doerr, Baerbel, Niebl, Peter, Dickneite, Gerhard

Journal:

Thrombosis Research

Year:

2015

Language:

english

File:

PDF, 373 KB

english, 2015

29

Antithrombin III in Animal Models of Sepsis and Organ Failure

Dickneite, Gerhard

Journal:

Seminars in Thrombosis and Hemostasis

Year:

1998

Language:

english

File:

PDF, 1.59 MB

english, 1998

30

Characterization of the Coagulation Deficit in Porcine Dilutional Coagulopathy and Substitution with a Prothrombin Complex Concentrate

Dickneite, Gerhard, Doerr, Baerbel, Kaspereit, Franz

Journal:

Anesthesia & Analgesia

Year:

2008

Language:

english

File:

PDF, 258 KB

english, 2008

31

Nonclinical analysis of the safety, pharmacodynamics, and pharmacokinetics of plasma-derived human FXIII concentrate in animals

Beyerle, Andrea, Solomon, Cristina, Dickneite, Gerhard, Herzog, Eva

Journal:

Pharmacology Research & Perspectives

Year:

2016

Language:

english

File:

PDF, 554 KB

english, 2016

32

The effect of fibrinogen concentrate administration on coagulation abnormalities in a rat sepsis model

Kaspereit, Franz, Doerr, Baerbel, Dickneite, Gerhard

Journal:

Blood Coagulation & Fibrinolysis

Year:

2004

Language:

english

File:

PDF, 104 KB

english, 2004

33

Local activation of Coagulation Factor XIII reduces systemic complications and improves the survival of mice after Streptococcus pyogenes M1 skin infection

Deicke, Christin, Chakrakodi, Bhavya, Pils, Marina C., Dickneite, Gerhard, Johansson, Linda, Medina, Eva, Loof, Torsten G.

Journal:

International Journal of Medical Microbiology

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

34

Animal model and clinical evidence indicating low thrombogenic potential of fibrinogen concentrate (Haemocomplettan P)

Dickneite, Gerhard, Pragst, Ingo, Joch, Christine, Bergman, Garrett E

Journal:

Blood Coagulation & Fibrinolysis

Year:

2009

Language:

english

File:

PDF, 332 KB

english, 2009

35

Utility of a high VWF

Raquet, Elmar, Stockschlaeder, Marcus, Mueller-Cohrs, Jochen, Zollner, Sabine, Pragst, Ingo, Dickneite, Gerhard

Journal:

Blood Coagulation & Fibrinolysis

Year:

2015

Language:

english

File:

PDF, 311 KB

english, 2015

36

Effective Reversal of Edoxaban-associated Bleeding with Four-factor Prothrombin Complex Concentrate in a Rabbit Model of Acute Hemorrhage

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mueller-Cohrs, Jochen, Pragst, Ingo, Morishima, Yoshiyuki, Dickneite, Gerhard

Journal:

Year:

2015

Language:

english

File:

PDF, 716 KB

english, 2015

37

FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis

May, Frauke, Krupka, Jennifer, Fries, Marion, Thielmann, Ina, Pragst, Ingo, Weimer, Thomas, Panousis, Con, Nieswandt, Bernhard, Stoll, Guido, Dickneite, Gerhard, Schulte, Stefan, Nolte, Marc W.

Journal:

British Journal of Haematology

Year:

2016

Language:

english

File:

PDF, 597 KB

english, 2016

38

Prothrombin Complex Concentrate Versus Recombinant Factor VIIa for Reversal of Hemodilutional Coagulopathy in a Porcine Trauma Model

Dickneite, Gerhard, Dörr, Bärbel, Kaspereit, Franz, Tanaka, Kenichi A.

Journal:

The Journal of Trauma Injury Infection and Critical Care

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

39

THE INFLUENCE OF ANTITHROMBIN III (AT III) ON EXPERIMENTAL SEPSIS

Dickneite, Gerhard

Journal:

Year:

1997

File:

PDF, 215 KB

1997

40

Cefodizime, an aminothiazolyl cephalosporin. IV. Influence on the immune system.

LIMBERT, MICHAEL, BARTLETT, ROBERT R., DICKNEITE, GERHARD, KLESEL, NORBERT, SCHORLEMMER, HANS ULRICH, SEIBERT, GERHARD, WINKLER, IRVIN, SCHRINNER, ELMAR

Journal:

The Journal of Antibiotics

Year:

1984

Language:

english

File:

PDF, 4.14 MB

english, 1984

41

Targeted inactivation of the mouse locus encoding coagulation factor XII-A: Hemostatic abnormalities in mutant mice and characterization of the coagulation deficit

Lauer, Peter, Metzner, Hubert J., Zettlmei\ss l, Gerd, Li, Meng, Smith, Austin G., Lathe, Richard, Dickneite, Gerhard

Journal:

Thrombosis and Haemostasis

Year:

2002

Language:

english

File:

PDF, 309 KB

english, 2002

42

Influence of Recombinant Hirudin on Tissue-Factor-Induced Activation of Coagulation in Rabbits

Kouz, Jalal, Czech, J&ouml, rg, Nicolay, Uwe, Dickneite, Gerhard

Journal:

Pathophysiology of Haemostasis and Thrombosis

Year:

1996

File:

PDF, 2.62 MB

1996

43

1528

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mischnik, Marcel, Pragst, Ingo, Dickneite, Gerhard

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 413 KB

english, 2016

44

1504

Herzog, Eva, Kaspereit, Franz, Krege, Wilfried, Doerr, Baerbel, Mischnik, Marcel, Pragst, Ingo, Dickneite, Gerhard

Journal:

Critical Care Medicine

Year:

2016

Language:

english

File:

PDF, 401 KB

english, 2016

45

Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice

Dardik, Rima, Leor, Jonathan, Skutelsky, Ehud, Castel, David, Holbova, Radka, Schiby, Ginette, Shaish, Aviv, Dickneite, Gerhard, Loscalzo, Joseph, Inbal, Aida

Journal:

Thrombosis and Haemostasis

Year:

2006

Language:

english

File:

PDF, 339 KB

english, 2006

46

The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats

Krupka, Jennifer, May, Frauke, Weimer, Thomas, Pragst, Ingo, Kleinschnitz, Christoph, Stoll, Guido, Panousis, Con, Dickneite, Gerhard, Nolte, Marc W., Meuth, Sven G.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.79 MB

english, 2016

47

Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence?

Dickneite, Gerhard, Hoffman, Maureane

Journal:

Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 767 KB

english, 2014

48

Targeted Inactivation of the Mouse Locus Encoding Coagulation Factor XIII-A: Hemostatic Abnormalities in Mutant Mice and Characterization of the Coagulation Deficit

Lauer, Peter, Metzner, Hubert, Zettlmeißl, Gerd, Li, Meng, Smith, Austin, Lathe, Richard, Dickneite, Gerhard

Journal:

Thrombosis and Haemostasis

Year:

2002

Language:

english

File:

PDF, 320 KB

english, 2002

49

Development of an Anti-Bleeding Agent for Recombinant Hirudin Induced Skin Bleeding in the Pig

Dickneite, Gerhard, Nicolay, Uwe, Friesen, Heinz-Jürgen, Reers, Martin

Journal:

Thrombosis and Haemostasis

Year:

1998

Language:

english

File:

PDF, 104 KB

english, 1998

50

Development of an Anti-Bleeding Agent for Recombinant Hirudin Induced Skin Bleeding in the Pig

Dickneite, Gerhard, Nicolay, Uwe, Friesen, Heinz-Jürgen, Reers, Martin

Journal:

Thrombosis and Haemostasis

Year:

1998

File:

PDF, 104 KB

1998